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Protective Efficacy in Sheep of Adenovirus-Vectored Vaccines against Bluetongue Virus Is Associated with Specific T Cell Responses.

Bluetongue virus (BTV) is an economically important Orbivirus of the Reoviridae family that causes a hemorrhagic disease in ruminants. Its control has been achieved by inactivated-vaccines that have proven to protect against homologous BTV challenge although unable to induce long-term immunity. Ther...

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Autores principales: Verónica Martín, Elena Pascual, Miguel Avia, Lourdes Peña, Félix Valcárcel, Noemí Sevilla
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science (PLoS) 2015-01-01
Colección:PLoS ONE
Acceso en línea:http://europepmc.org/articles/PMC4664254?pdf=render
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