Vaccination with Recombinant Adenoviruses Expressing the Peste des Petits Ruminants Virus F or H Proteins Overcomes Viral Immunosuppression and Induces Protective Immunity against PPRV Challenge in Sheep

Peste des petits ruminants (PPR) is a highly contagious disease of small ruminants caused by the Morbillivirus peste des petits ruminants virus (PPRV). Two recombinant replication-defective human adenoviruses serotype 5 (Ad5) expressing either the highly immunogenic fusion protein (F) or hemagglutin...

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Detalhes bibliográficos
Main Authors: Rojas, José M., Moreno, Héctor, Valcárcel, Félix, Peña, Lourdes, Sevilla, Noemí, Martín, Verónica
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4094465/
https://ncbi.nlm.nih.gov/pubmed/25013961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0101226
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