Novel Analysis Software for Detecting and Classifying Ca2+ Transient Abnormalities in Stem Cell-Derived Cardiomyocytes.

Comprehensive functioning of Ca2+ cycling is crucial for excitation-contraction coupling of cardiomyocytes (CMs). Abnormal Ca2+ cycling is linked to arrhythmogenesis, which is associated with cardiac disorders and heart failure. Accordingly, we have generated spontaneously beating CMs from induced p...

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Bibliographic Details
Main Authors: Kirsi Penttinen, Harri Siirtola, Jorge Àvalos-Salguero, Tiina Vainio, Martti Juhola, Katriina Aalto-Setälä
Format: Artigo
Language:Inglês
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4550257?pdf=render
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