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Simultaneous recordings of action potentials and calcium transients from human induced pluripotent stem cell derived cardiomyocytes

Human induced pluripotent stem cell derived cardiomyocytes (hiPSC-CMs) offer a unique in vitro platform to study cardiac diseases, as they recapitulate many disease phenotypes. The membrane potential (V(m)) and intracellular calcium (Ca(2+)) transient (CaT) are usually investigated separately, becau...

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Detalhes bibliográficos
Publicado no:Biol Open
Main Authors: Prajapati, Chandra, Pölönen, Risto-Pekka, Aalto-Setälä, Katriina
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6078349/
https://ncbi.nlm.nih.gov/pubmed/29970475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.035030
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