Direct Reprogramming of Mouse Fibroblasts into Functional Skeletal Muscle Progenitors

Summary: Skeletal muscle harbors quiescent stem cells termed satellite cells and proliferative progenitors termed myoblasts, which play pivotal roles during muscle regeneration. However, current technology does not allow permanent capture of these cell populations in vitro. Here, we show that ectopi...

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Main Authors: Ori Bar-Nur, Mattia F.M. Gerli, Bruno Di Stefano, Albert E. Almada, Amy Galvin, Amy Coffey, Aaron J. Huebner, Peter Feige, Cassandra Verheul, Priscilla Cheung, Duygu Payzin-Dogru, Sylvain Paisant, Anthony Anselmo, Ruslan I. Sadreyev, Harald C. Ott, Shahragim Tajbakhsh, Michael A. Rudnicki, Amy J. Wagers, Konrad Hochedlinger
Formáid: Artigo
Teanga:Inglês
Foilsithe: Elsevier 2018-05-01
Sraith:Stem Cell Reports
Rochtain Ar Líne:http://www.sciencedirect.com/science/article/pii/S2213671118301772
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