Direct Reprogramming of Mouse Fibroblasts into Functional Skeletal Muscle Progenitors

Summary: Skeletal muscle harbors quiescent stem cells termed satellite cells and proliferative progenitors termed myoblasts, which play pivotal roles during muscle regeneration. However, current technology does not allow permanent capture of these cell populations in vitro. Here, we show that ectopi...

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Autores principales: Ori Bar-Nur, Mattia F.M. Gerli, Bruno Di Stefano, Albert E. Almada, Amy Galvin, Amy Coffey, Aaron J. Huebner, Peter Feige, Cassandra Verheul, Priscilla Cheung, Duygu Payzin-Dogru, Sylvain Paisant, Anthony Anselmo, Ruslan I. Sadreyev, Harald C. Ott, Shahragim Tajbakhsh, Michael A. Rudnicki, Amy J. Wagers, Konrad Hochedlinger
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2018-05-01
Colección:Stem Cell Reports
Acceso en línea:http://www.sciencedirect.com/science/article/pii/S2213671118301772
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