Characterization of Hematopoiesis in Sickle Cell Disease by Prospective Isolation of Stem and Progenitor Cells

The consequences of sickle cell disease (SCD) include ongoing hematopoietic stress, hemolysis, vascular damage, and effect of chronic therapies, such as blood transfusions and hydroxyurea, on hematopoietic stem and progenitor cell (HSPC) have been poorly characterized. We have quantified the frequen...

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Detalhes bibliográficos
Main Authors: Seda S. Tolu, Kai Wang, Zi Yan, Shouping Zhang, Karl Roberts, Andrew S. Crouch, Gracy Sebastian, Mark Chaitowitz, Eric D. Fornari, Evan M. Schwechter, Joan Uehlinger, Deepa Manwani, Caterina P. Minniti, Eric E. Bouhassira
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2020-09-01
Colecção:Cells
Assuntos:
sickle cell disease
hematopoietic stem cells
hydroxyurea
transfusion
Acesso em linha:https://www.mdpi.com/2073-4409/9/10/2159
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