From Form to Function: The role of Nox4 in the Cardiovascular System

The NADPH oxidase (Nox) family of proteins is comprised of 7 members, including Noxes 1-5 and the Duoxes 1 and 2. Nox4 is readily distinguished from the other Nox isoforms by its high level of expression in cardiovascular tissues and unique enzymatic properties. Nox4 is constitutively active and the...

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Detalhes bibliográficos
Main Authors: Feng eChen, Stephen eHaigh, Scott A Barman, David eFulton
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2012-11-01
Colecção:Frontiers in Physiology
Assuntos:
NADPH Oxidase
Reactive Oxygen Species
NOX4
Subcellular localization
H2O2
cardiovascular disease.
Acesso em linha:http://journal.frontiersin.org/Journal/10.3389/fphys.2012.00412/full
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