NOX4-dependent Hydrogen Peroxide Overproduction in Human Atrial Fibrillation and HL-1 Atrial Cells: Relationship to Hypertension

Background/Objectives: Atrial fibrillation (AF) is the most common type of cardiac arrhythmia with patients dying frequently of stroke. In view of the unclear etiologies of AF and a potential role of oxidative stress, the present study examined cardiac ROS production and NADPH oxidase (NOX) express...

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Detalhes bibliográficos
Main Authors: Jun eZhang, Ji Youn eYoun, Antony eKim, Rafael eRamire, Ling eGao, Doan eNgo, Jennifer eScovotti, Aman eMahajan, Hua Linda Cai
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2012-06-01
Colecção:Frontiers in Physiology
Assuntos:
Angiotensin II
Hypertension
NADPH Oxidase
atrial fibrillation (AF)
hydrogen peroxide (H2O2)
NOX4
Acesso em linha:http://journal.frontiersin.org/Journal/10.3389/fphys.2012.00140/full
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