A screening system to identify transcription factors that induce binding site-directed DNA demethylation

Abstract Background DNA methylation is a fundamental epigenetic modification that is involved in many biological systems such as differentiation and disease. We and others recently showed that some transcription factors (TFs) are involved in the site-specific determination of DNA demethylation in a...

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Main Authors: Takahiro Suzuki, Shiori Maeda, Erina Furuhata, Yuri Shimizu, Hajime Nishimura, Mami Kishima, Harukazu Suzuki
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2017-12-01
Colecção:Epigenetics & Chromatin
Assuntos:
DNA demethylation
Transcription factor
Binding site
Acesso em linha:http://link.springer.com/article/10.1186/s13072-017-0169-6
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