Scleral HIF-1α is a prominent regulatory candidate for genetic and environmental interactions in human myopia pathogenesis

Background: Myopia is a good model for understanding the interaction between genetics and environmental stimuli. Here we dissect the biological processes affecting myopia progression. Methods: Human Genetic Analyses: (1) gene set analysis (GSA) of new genome wide association study (GWAS) data for 59...

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Библиографические подробности
Главные авторы: Fei Zhao, Dake Zhang, Qingyi Zhou, Fuxin Zhao, Mingguang He, Zhenglin Yang, Yongchao Su, Ying Zhai, Jiaofeng Yan, Guoyun Zhang, Anquan Xue, Jing Tang, Xiaotong Han, Yi Shi, Yun Zhu, Tianzi Liu, Wenjuan Zhuang, Lulin Huang, Yaqiang Hong, Deng Wu, Yingxiang Li, Qinkang Lu, Wei Chen, Shiming Jiao, Qiongsi Wang, Nethrajeith Srinivasalu, Yingying Wen, Changqing Zeng, Jia Qu, Xiangtian Zhou
Формат: Artigo
Язык:Inglês
Опубликовано: Elsevier 2020-07-01
Серии:EBioMedicine
Предметы:
Genetic and environmental interactions
Myopia
Sclera
Near work
Myopia risk genes
HIF-1α
Online-ссылка:http://www.sciencedirect.com/science/article/pii/S235239642030253X
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