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Intronic alternative splicing regulators identified by comparative genomics in nematodes.

Many alternative splicing events are regulated by pentameric and hexameric intronic sequences that serve as binding sites for splicing regulatory factors. We hypothesized that intronic elements that regulate alternative splicing are under selective pressure for evolutionary conservation. Using a Wob...

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Bibliographic Details
Main Authors: Jennifer L Kabat, Sergio Barberan-Soler, Paul McKenna, Hiram Clawson, Tracy Farrer, Alan M Zahler
Format: Artigo
Language:Inglês
Published: Public Library of Science (PLoS) 2006-07-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC1500816?pdf=render
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