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Simultaneous gene silencing of Bcl-2, XIAP and Survivin re-sensitizes pancreatic cancer cells towards apoptosis

<p>Abstract</p> <p>Background</p> <p>Pancreatic ductal adenocarcinoma shows a distinct apoptosis resistance, which contributes significantly to the aggressive nature of this tumor and constrains the effectiveness of new therapeutic strategies. Apoptosis resistance is de...

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Huvudupphovsmän: Grützmann Robert, Saeger Hans-Detlev, Lehner Anne-Kathrin, Samm Nicole, Rückert Felix, Pilarsky Christian
Materialtyp: Artigo
Språk:Inglês
Publicerad: BMC 2010-07-01
Serie:BMC Cancer
Länkar:http://www.biomedcentral.com/1471-2407/10/379
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