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Oxazaphosphorine bioactivation and detoxification: the role of xenobiotic receptors

Oxazaphosphorines, with the most representative members including cyclophosphamide, ifosfamide, and trofosfamide, constitute a class of alkylating agents that have a broad spectrum of anticancer activity against many malignant ailments including both solid tumors such as breast cancer and hematologi...

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Bibliografski detalji
Glavni autori: Duan Wang, Hongbing Wang
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2012-04-01
Serija:Acta Pharmaceutica Sinica B
Teme:
CAR
PXR
Online pristup:http://www.sciencedirect.com/science/article/pii/S2211383512000202
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