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Age-related DNA methylation changes are tissue-specific with ELOVL2 promoter methylation as exception

Abstract Background The well-established association of chronological age with changes in DNA methylation is primarily founded on the analysis of large sets of blood samples, while conclusions regarding tissue-specificity are typically based on small number of samples, tissues and CpGs. Here, we sys...

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Detalhes bibliográficos
Main Authors: Roderick C. Slieker, Caroline L. Relton, Tom R. Gaunt, P. Eline Slagboom, Bastiaan T. Heijmans
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2018-05-01
Colecção:Epigenetics & Chromatin
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Acesso em linha:http://link.springer.com/article/10.1186/s13072-018-0191-3
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