Quantifying missing heritability at known GWAS loci.

Recent work has shown that much of the missing heritability of complex traits can be resolved by estimates of heritability explained by all genotyped SNPs. However, it is currently unknown how much heritability is missing due to poor tagging or additional causal variants at known GWAS loci. Here, we...

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Главные авторы: Alexander Gusev, Gaurav Bhatia, Noah Zaitlen, Bjarni J Vilhjalmsson, Dorothée Diogo, Eli A Stahl, Peter K Gregersen, Jane Worthington, Lars Klareskog, Soumya Raychaudhuri, Robert M Plenge, Bogdan Pasaniuc, Alkes L Price
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science (PLoS) 2013-01-01
Серии:PLoS Genetics
Online-ссылка:http://europepmc.org/articles/PMC3873246?pdf=render
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