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Quantifying missing heritability at known GWAS loci.

Recent work has shown that much of the missing heritability of complex traits can be resolved by estimates of heritability explained by all genotyped SNPs. However, it is currently unknown how much heritability is missing due to poor tagging or additional causal variants at known GWAS loci. Here, we...

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書誌詳細
主要な著者: Alexander Gusev, Gaurav Bhatia, Noah Zaitlen, Bjarni J Vilhjalmsson, Dorothée Diogo, Eli A Stahl, Peter K Gregersen, Jane Worthington, Lars Klareskog, Soumya Raychaudhuri, Robert M Plenge, Bogdan Pasaniuc, Alkes L Price
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science (PLoS) 2013-01-01
シリーズ:PLoS Genetics
オンライン・アクセス:http://europepmc.org/articles/PMC3873246?pdf=render
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