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The histone chaperone HIRA promotes the induction of host innate immune defences in response to HSV-1 infection.
Host innate immune defences play a critical role in restricting the intracellular propagation and pathogenesis of invading viral pathogens. Here we show that the histone H3.3 chaperone HIRA (histone cell cycle regulator) associates with promyelocytic leukaemia nuclear bodies (PML-NBs) to stimulate t...
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| 主要な著者: | , , , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Public Library of Science (PLoS)
2019-03-01
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| シリーズ: | PLoS Pathogens |
| オンライン･アクセス: | https://doi.org/10.1371/journal.ppat.1007667 |
| タグ: |
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