The Role of Nonapoptotic Programmed Cell Death — Ferroptosis, Necroptosis, and Pyroptosis — in Pancreatic Ductal Adenocarcinoma Treatment

Pancreatic ductal adenocarcinoma (PDAC) is the most lethal cancer, with a dismal 5-year survival rate of less than 10%. It is estimated that approximately 80% of pancreatic ductal carcinoma (PDAC) patients are diagnosed at an advanced or metastatic stage. Hence, most patients are not appropriate can...

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Main Authors: Sheng-Kai Hsu, Yi-Hsuan Chu, Wun-Jyun Syue, Hugo You-Hsien Lin, Wen-Tsan Chang, Jeff Yi-Fu Chen, Chang-Yi Wu, Chia-Hung Yen, Kai-Chun Cheng, Chien-Chih Chiu
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2022-05-01
Colecção:Frontiers in Oncology
Assuntos:
pancreatic ductal adenocarcinoma (PDAC)
antiapoptotic effect
chemoresistance
ferroptosis
necroptosis
pyroptosis
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fonc.2022.872883/full
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