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The Mechanism of Ferroptosis and Applications in Tumor Treatment
Iron-dependent ferroptosis is a new form of cell death in recent years, which is driven by lipid peroxidation. The lethal lipid accumulation caused by glutathione depletion or inactivation of glutathione peroxidase 4 (GPX4) is characteristic of the ferroptosis process. In recent years, with the in-d...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Frontiers Media S.A.
2020-07-01
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| Schriftenreihe: | Frontiers in Pharmacology |
| Schlagworte: | |
| Online Zugang: | https://www.frontiersin.org/article/10.3389/fphar.2020.01061/full |
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