Strategy for Development of Site-Specific Ubiquitin Antibodies

Protein ubiquitination is a key post-translational modification regulating a wide range of biological processes. Ubiquitination involves the covalent attachment of the small protein ubiquitin to a lysine of a protein substrate. In addition to its well-established role in protein degradation, protein...

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Main Authors: Ila van Kruijsbergen, Monique P. C. Mulder, Michael Uckelmann, Tibor van Welsem, John de Widt, Aldo Spanjaard, Heinz Jacobs, Farid El Oualid, Huib Ovaa, Fred van Leeuwen
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2020-02-01
Serier:Frontiers in Chemistry
Fag:
ubiquitin
histone H2B
H2B-K123ub
PCNA
monoclonal antibody
Online adgang:https://www.frontiersin.org/article/10.3389/fchem.2020.00111/full
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