Trans-Ethnic Mapping of BANK1 Identifies Two Independent SLE-Risk Linkage Groups Enriched for Co-Transcriptional Splicing Marks

BANK1 is a susceptibility gene for several systemic autoimmune diseases in several populations. Using the genome-wide association study (GWAS) data from Europeans (EUR) and African Americans (AA), we performed an extensive fine mapping of ankyrin repeats 1 (BANK1). To increase the SNP density, we us...

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Autori principali: Manuel Martínez-Bueno, Nina Oparina, Mikhail G. Dozmorov, Miranda C. Marion, Mary E. Comeau, Gary Gilkeson, Diane Kamen, Michael Weisman, Jane Salmon, Joseph W. McCune, John B. Harley, Robert Kimberly, Judith A. James, Joan Merrill, Courtney Montgomery, Carl D. Langefeld, Marta E. Alarcón-Riquelme
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI AG 2018-08-01
Serie:International Journal of Molecular Sciences
Soggetti:
autoimmune disorders
systemic lupus erythematosus
genetics
BANK1
transethnic genetic studies
Accesso online:http://www.mdpi.com/1422-0067/19/8/2331
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