The Pfs230 N-terminal fragment, Pfs230D1+: expression and characterization of a potential malaria transmission-blocking vaccine candidate

Abstract Background Control and elimination of malaria can be accelerated by transmission-blocking interventions such as vaccines. A surface antigen of Plasmodium falciparum gametocytes, Pfs230, is a leading vaccine target antigen, and has recently progressed to experimental clinical trials. To supp...

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Hlavní autoři: Shwu-Maan Lee, Yimin Wu, John M. Hickey, Kazutoyo Miura, Neal Whitaker, Sangeeta B. Joshi, David B. Volkin, C. Richter King, Jordan Plieskatt
Médium: Artigo
Jazyk:Inglês
Vydáno: BMC 2019-11-01
Edice:Malaria Journal
Témata:
Malaria
Pfs230
Plasmodium falciparum
Transmission-blocking vaccine
Baculovirus
Glycosylation
On-line přístup:http://link.springer.com/article/10.1186/s12936-019-2989-2
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