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Expression and purification optimization of an N-terminal Pfs230 transmission-blocking vaccine candidate

In an effort to control and eventually eliminate malaria, the development of transmission-blocking vaccines has long been sought. However, few antigens have been evaluated in clinical trials, often due to limitations in the expression and purification of the antigen in sufficient yield and quality....

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Détails bibliographiques
Publié dans:Protein Expr Purif
Auteurs principaux: Lee, Shwu-Maan, Plieskatt, Jordan, Krishnan, Seetha, Raina, Monika, Harishchandra, Rakeshkumar, King, C. Richter
Format: Artigo
Langue:Inglês
Publié: Academic Press 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6547048/
https://ncbi.nlm.nih.gov/pubmed/30978392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pep.2019.04.001
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