Generation of a human iPSC line CIBi010-A with a reporter for ASGR1 using CRISPR/Cas9

ASGR1 is a liver-specific surface marker that has been used to purify human pluripotent stem cell (PSC)-derived hepatocytes (iHeps). Furthermore, ASGR1+ iHeps represents a more mature subpopulation of iHeps. To utilize this marker for optimizing iHep differentiation and purification, we substituted...

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Autores principales: Jian Fu, Lixiang Jiang, Baorong Yu, Yuqing Liu, Rui Wei, Yang Hu, Wai-In Ho, Bo Yang, Meng Chu, Hung-Fat Tse, Jiayin Yang
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2022-07-01
Colección:Stem Cell Research
Acceso en línea:http://www.sciencedirect.com/science/article/pii/S1873506122001490
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