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Artificial hybrids of influenza A virus RNA polymerase reveal PA subunit modulates its thermal sensitivity.
BACKGROUND: Influenza A virus can infect a variety of different hosts and therefore has to adapt to different host temperatures for its efficient viral replication. Influenza virus codes for an RNA polymerase of 3 subunits: PB1, PB2 and PA. It is well known that the PB2 subunit is involved in temper...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Public Library of Science (PLoS)
2010-01-01
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| Серии: | PLoS ONE |
| Online-ссылка: | http://europepmc.org/articles/PMC2998429?pdf=render |
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