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A paralogous pair of mammalian host restriction factors form a critical host barrier against poxvirus infection.

Host restriction factors constitute a formidable barrier for viral replication to which many viruses have evolved counter-measures. Human SAMD9, a tumor suppressor and a restriction factor for poxviruses in cell lines, is antagonized by two classes of poxvirus proteins, represented by vaccinia virus...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Xiangzhi Meng, Fushun Zhang, Bo Yan, Chuanping Si, Hiroaki Honda, Akiko Nagamachi, Lu-Zhe Sun, Yan Xiang
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science (PLoS) 2018-02-01
Cyfres:PLoS Pathogens
Mynediad Ar-lein:http://europepmc.org/articles/PMC5831749?pdf=render
Tagiau: Ychwanegu Tag
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