A paralogous pair of mammalian host restriction factors form a critical host barrier against poxvirus infection.

Host restriction factors constitute a formidable barrier for viral replication to which many viruses have evolved counter-measures. Human SAMD9, a tumor suppressor and a restriction factor for poxviruses in cell lines, is antagonized by two classes of poxvirus proteins, represented by vaccinia virus...

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Main Authors: Xiangzhi Meng, Fushun Zhang, Bo Yan, Chuanping Si, Hiroaki Honda, Akiko Nagamachi, Lu-Zhe Sun, Yan Xiang
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science (PLoS) 2018-02-01
סדרה:PLoS Pathogens
גישה מקוונת:http://europepmc.org/articles/PMC5831749?pdf=render
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