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Hypoxia inducible factor signaling modulates susceptibility to mycobacterial infection via a nitric oxide dependent mechanism.

Tuberculosis is a current major world-health problem, exacerbated by the causative pathogen, Mycobacterium tuberculosis (Mtb), becoming increasingly resistant to conventional antibiotic treatment. Mtb is able to counteract the bactericidal mechanisms of leukocytes to survive intracellularly and deve...

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Detalhes bibliográficos
Main Authors: Philip M Elks, Sabrina Brizee, Michiel van der Vaart, Sarah R Walmsley, Fredericus J van Eeden, Stephen A Renshaw, Annemarie H Meijer
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2013-01-01
Colecção:PLoS Pathogens
Acesso em linha:http://europepmc.org/articles/PMC3868520?pdf=render
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