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Design of phase II non-inferiority trials

With the development of inexpensive treatment regimens and less invasive surgical procedures, we are confronted with non-inferiority study objectives. A non-inferiority phase III trial requires a roughly four times larger sample size than that of a similar standard superiority trial. Because of the...

詳細記述

保存先:
書誌詳細
第一著者: Sin-Ho Jung
フォーマット: Artigo
言語:Inglês
出版事項: Elsevier 2017-09-01
シリーズ:Contemporary Clinical Trials Communications
オンライン・アクセス:http://www.sciencedirect.com/science/article/pii/S245186541630134X
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