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Design of phase II non-inferiority trials

With the development of inexpensive treatment regimens and less invasive surgical procedures, we are confronted with non-inferiority study objectives. A non-inferiority phase III trial requires a roughly four times larger sample size than that of a similar standard superiority trial. Because of the...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awdur: Sin-Ho Jung
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Elsevier 2017-09-01
Cyfres:Contemporary Clinical Trials Communications
Mynediad Ar-lein:http://www.sciencedirect.com/science/article/pii/S245186541630134X
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