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HM71224, a selective Bruton’s tyrosine kinase inhibitor, attenuates the development of murine lupus
Abstract Background Systemic lupus erythematosus (SLE) is associated with B cell hyperactivity, and lupus nephritis (LN), in particular, is promoted by the production of autoantibodies and immune complex deposition. Bruton’s tyrosine kinase (BTK) plays critical roles in B cell receptor-related and F...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BMC
2017-09-01
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| Colecção: | Arthritis Research & Therapy |
| Acesso em linha: | http://link.springer.com/article/10.1186/s13075-017-1402-1 |
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