Determination of neuraminidase kinetic constants using whole influenza virus preparations and correction for spectroscopic interference by a fluorogenic substrate.

The influenza neuraminidase (NA) enzyme cleaves terminal sialic acid residues from cellular receptors, a process required for the release of newly synthesized virions. A balance of NA activity with sialic acid binding affinity of hemagglutinin (HA) is important for optimal virus replication. NA sequ...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Bindumadhav M Marathe, Vincent Lévêque, Klaus Klumpp, Robert G Webster, Elena A Govorkova
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science (PLoS) 2013-01-01
Серии:PLoS ONE
Online-ссылка:http://europepmc.org/articles/PMC3744557?pdf=render
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы