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Association of Human iPSC Gene Signatures and X Chromosome Dosage with Two Distinct Cardiac Differentiation Trajectories

Summary: Despite the importance of understanding how variability across induced pluripotent stem cell (iPSC) lines due to non-genetic factors (clone and passage) influences their differentiation outcome, large-scale studies capable of addressing this question have not yet been conducted. Here, we di...

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Detalhes bibliográficos
Main Authors: Agnieszka D'Antonio-Chronowska, Margaret K.R. Donovan, William W. Young Greenwald, Jennifer Phuong Nguyen, Kyohei Fujita, Sherin Hashem, Hiroko Matsui, Francesca Soncin, Mana Parast, Michelle C. Ward, Florence Coulet, Erin N. Smith, Eric Adler, Matteo D'Antonio, Kelly A. Frazer
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019-11-01
Colecção:Stem Cell Reports
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2213671119303613
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