Impact of Age and HIV Status on Immune Activation, Senescence and Apoptosis

IntroductionResidual immune dysfunctions, resembling those that occur during normal aging, may persist even in well-treated people with HIV (PWH), and accelerated aging has been proposed. We aimed to determine if HIV infection is an independent risk factor for T-cell immune dysfunctions including in...

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Detalhes bibliográficos
Main Authors: Malene Hove-Skovsgaard, Yanan Zhao, Jeanette Linnea Tingstedt, Hans Jakob Hartling, Rebekka Faber Thudium, Thomas Benfield, Shoaib Afzal, Børge Nordestgaard, Henrik Ullum, Jan Gerstoft, Amanda Mocroft, Susanne Dam Nielsen
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020-09-01
Colecção:Frontiers in Immunology
Assuntos:
HIV infection
flow cytometry
T-cells
immune activation
immune senescence
aging
Acesso em linha:https://www.frontiersin.org/article/10.3389/fimmu.2020.583569/full
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