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The role of structural dynamics of actin in class-specific myosin motility.

The structural dynamics of actin, including the tilting motion between the small and large domains, are essential for proper interactions with actin-binding proteins. Gly146 is situated at the hinge between the two domains, and we previously showed that a G146V mutation leads to severe motility defe...

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Main Authors: Taro Q P Noguchi, Masatoshi Morimatsu, Atsuko H Iwane, Toshio Yanagida, Taro Q P Uyeda
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science (PLoS) 2015-01-01
Sraith:PLoS ONE
Rochtain Ar Líne:http://europepmc.org/articles/PMC4422724?pdf=render
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