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Hydrogen sulfide releasing aspirin, ACS14, attenuates high glucose-induced increased methylglyoxal and oxidative stress in cultured vascular smooth muscle cells.

Hydrogen sulfide is a gasotransmitter with vasodilatory and anti-inflammatory properties. Aspirin is an irreversible cyclooxygenase inhibitor anti-inflammatory drug. ACS14 is a novel synthetic hydrogen sulfide releasing aspirin which inhibits cyclooxygenase and has antioxidant effects. Methylglyoxal...

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Bibliografische gegevens
Hoofdauteurs: Qian Huang, Anna Sparatore, Piero Del Soldato, Lingyun Wu, Kaushik Desai
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science (PLoS) 2014-01-01
Reeks:PLoS ONE
Online toegang:http://europepmc.org/articles/PMC4045575?pdf=render
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