Inhibition of (Pro)renin Receptor-Mediated Oxidative Stress Alleviates Doxorubicin-Induced Heart Failure

AimClinical utility of doxorubicin (DOX) is limited by its cardiotoxic side effect, and the underlying mechanism still needs to be fully elucidated. This research aimed to examine the role of (pro)renin receptor (PRR) in DOX-induced heart failure (HF) and its underlying mechanism.Main MethodsSprague...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Xiao-yi Du, Dao-chun Xiang, Ping Gao, Hua Peng, Ya-li Liu
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Frontiers Media S.A. 2022-04-01
Saila:Frontiers in Oncology
Gaiak:
doxorubicin
cardiotoxicity
heart failure
(Pro) renin receptor
RAC1
Sarrera elektronikoa:https://www.frontiersin.org/articles/10.3389/fonc.2022.874852/full
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