A Clinical-Genetic Score to Identify Surgically Resected Colorectal Cancer Patients Benefiting From an Adjuvant Fluoropyrimidine-Based Therapy

There are clinical challenges related to adjuvant treatment in colorectal cancer (CRC) and novel molecular markers are needed for better risk stratification of patients. Our aim was to integrate our previously reported clinical-genetic prognostic score with new immunogenetic markers of 5-year diseas...

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Auteurs principaux: Elena De Mattia, Eva Dreussi, Marcella Montico, Sara Gagno, Chiara Zanusso, Luca Quartuccio, Salvatore De Vita, Michela Guardascione, Angela Buonadonna, Mario D’Andrea, Nicoletta Pella, Adolfo Favaretto, Enrico Mini, Stefania Nobili, Loredana Romanato, Erika Cecchin, Giuseppe Toffoli
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2018-10-01
Collection:Frontiers in Pharmacology
Sujets:
colorectal cancer
fluoropyrimidines
interferon-γ
immune system
immunogenetics
adjuvant treatment
Accès en ligne:https://www.frontiersin.org/article/10.3389/fphar.2018.01101/full
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