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Evaluation of the stability, bioavailability, and hypersensitivity of the omega-3 derived anti-leukemic prostaglandin: Δ(12)-prostaglandin J3.

Previous studies have demonstrated the ability of an eicosapentaenoic acid (EPA)-derived endogenous cyclopentenone prostaglandin (CyPG) metabolite, Δ(12)-PGJ3, to selectively target leukemic stem cells, but not the normal hematopoietic stems cells, in in vitro and in vivo models of chronic myelogeno...

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Main Authors: Avinash K Kudva, Naveen Kaushal, Sonia Mohinta, Mary J Kennett, Avery August, Robert F Paulson, K Sandeep Prabhu
格式: Artigo
語言:Inglês
出版: Public Library of Science (PLoS) 2013-01-01
叢編:PLoS ONE
在線閱讀:http://europepmc.org/articles/PMC3846793?pdf=render
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