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Evaluation of the stability, bioavailability, and hypersensitivity of the omega-3 derived anti-leukemic prostaglandin: Δ(12)-prostaglandin J3.
Previous studies have demonstrated the ability of an eicosapentaenoic acid (EPA)-derived endogenous cyclopentenone prostaglandin (CyPG) metabolite, Δ(12)-PGJ3, to selectively target leukemic stem cells, but not the normal hematopoietic stems cells, in in vitro and in vivo models of chronic myelogeno...
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Hauptverfasser: | , , , , , , |
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Format: | Artigo |
Sprache: | Inglês |
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Public Library of Science (PLoS)
2013-01-01
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Schriftenreihe: | PLoS ONE |
Online Zugang: | http://europepmc.org/articles/PMC3846793?pdf=render |
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