Analysis of the CDK4/6 Cell Cycle Pathway in Leiomyosarcomas as a Potential Target for Inhibition by Palbociclib

Leiomyosarcoma (LMS) is characterized by high genomic complexity, and to date, no specific targeted therapy is available. In a genome-wide approach, we profiled genomic aberrations in a small cohort of eight primary tumours, two relapses, and eight metastases across nine different patients. We ident...

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Detaylı Bibliyografya
Asıl Yazarlar: Michael J. Böhm, Ralf Marienfeld, Daniela Jäger, Kevin Mellert, Adrian von Witzleben, Silke Brüderlein, Mathias Wittau, Alexandra von Baer, Markus Schultheiss, Regine Mayer-Steinacker, Frank G. Rücker, Peter Möller, Lars Bullinger, Thomas F. E. Barth
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Hindawi Limited 2019-01-01
Seri Bilgileri:Sarcoma
Online Erişim:http://dx.doi.org/10.1155/2019/3914232
Etiketler: Etiketle
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