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Accurate multiple sequence alignment of transmembrane proteins with PSI-Coffee

<p>Abstract</p> <p>Background</p> <p>Transmembrane proteins (TMPs) constitute about 20~30% of all protein coding genes. The relative lack of experimental structure has so far made it hard to develop specific alignment methods and the current state of the art (PRALINE™)...

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Main Authors: Chang Jia-Ming, Di Tommaso Paolo, Taly Jean-François, Notredame Cedric
格式: Artigo
語言:Inglês
出版: BMC 2012-03-01
叢編:BMC Bioinformatics
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