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Accurate multiple sequence alignment of transmembrane proteins with PSI-Coffee

BACKGROUND: Transmembrane proteins (TMPs) constitute about 20~30% of all protein coding genes. The relative lack of experimental structure has so far made it hard to develop specific alignment methods and the current state of the art (PRALINE™) only manages to recapitulate 50% of the positions in th...

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Bibliografiske detaljer
Main Authors: Chang, Jia-Ming, Di Tommaso, Paolo, Taly, Jean-François, Notredame, Cedric
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3303701/
https://ncbi.nlm.nih.gov/pubmed/22536955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-13-S4-S1
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