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BRAF and MEK Inhibitors Influence the Function of Reprogrammed T Cells: Consequences for Adoptive T-Cell Therapy
BRAF and MEK inhibitors (BRAFi/MEKi), the standard treatment for patients with BRAFV600 mutated melanoma, are currently explored in combination with various immunotherapies, notably checkpoint inhibitors and adoptive transfer of receptor-transfected T cells. Since two BRAFi/MEKi combinations with si...
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Main Authors: | , , , , , , |
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Format: | Artigo |
Jezik: | Inglês |
Izdano: |
MDPI AG
2018-01-01
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Serija: | International Journal of Molecular Sciences |
Teme: | |
Online dostop: | http://www.mdpi.com/1422-0067/19/1/289 |
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