Phenoconversion of Cytochrome P450 Metabolism: A Systematic Review

Phenoconversion is the mismatch between the individual’s genotype-based prediction of drug metabolism and the true capacity to metabolize drugs due to nongenetic factors. While the concept of phenoconversion has been described in narrative reviews, no systematic review is available. A systematic rev...

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Main Authors: Sylvia D. Klomp, Martijn L. Manson, Henk-Jan Guchelaar, Jesse J. Swen
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2020-09-01
Serier:Journal of Clinical Medicine
Fag:
phenoconversion
pharmacogenetics
cytochrome P450
concomitant medication
comorbidities
<i>CYP2D6</i>
Online adgang:https://www.mdpi.com/2077-0383/9/9/2890
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