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The structure-function analysis of the Mpr1 metalloprotease determinants of activity during migration of fungal cells across the blood-brain barrier.

Cryptococcal meningoencephalitis, the most common form of cryptococcosis, is caused by the opportunistic fungal pathogen, Cryptococcus neoformans. Molecular strategies used by C. neoformans to invade the central nervous system (CNS) have been the focus of several studies. Recently, the role of a nov...

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Main Authors: Sarisa Na Pombejra, Mantana Jamklang, John P Uhrig, Kiem Vu, Angie Gelli
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Acceso en liña:http://europepmc.org/articles/PMC6117016?pdf=render
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