Invasion of the Central Nervous System by Cryptococcus neoformans Requires a Secreted Fungal Metalloprotease

Cryptococcus spp. cause life-threatening fungal infection of the central nervous system (CNS), predominantly in patients with a compromised immune system. Why Cryptococcus neoformans has this remarkable tropism for the CNS is not clear. Recent research on cerebral pathogenesis of C. neoformans revea...

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Main Authors: Vu, Kiem, Tham, Rick, Uhrig, John P., Thompson, George R., Na Pombejra, Sarisa, Jamklang, Mantana, Bautos, Jennifer M., Gelli, Angie
Format: Artigo
Jezik:Inglês
Izdano: American Society of Microbiology 2014
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4049100/
https://ncbi.nlm.nih.gov/pubmed/24895304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01101-14
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