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Response surface methodology and process optimization of sustained release pellets using Taguchi orthogonal array design and central composite design

Furosemide is a powerful diuretic and antihypertensive drug which has low bioavailability due to hepatic first pass metabolism and has a short half-life of 2 hours. To overcome the above drawback, the present study was carried out to formulate and evaluate sustained release (SR) pellets of furosemid...

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Detalhes bibliográficos
Main Authors: Gurinder Singh, Roopa S Pai, V Kusum Devi
Formato: Artigo
Idioma:Inglês
Publicado em: Wolters Kluwer Medknow Publications 2012-01-01
Colecção:Journal of Advanced Pharmaceutical Technology & Research
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Acesso em linha:http://www.japtr.org/article.asp?issn=2231-4040;year=2012;volume=3;issue=1;spage=30;epage=40;aulast=Singh
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