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Response surface methodology and process optimization of sustained release pellets using Taguchi orthogonal array design and central composite design
Furosemide is a powerful diuretic and antihypertensive drug which has low bioavailability due to hepatic first pass metabolism and has a short half-life of 2 hours. To overcome the above drawback, the present study was carried out to formulate and evaluate sustained release (SR) pellets of furosemid...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Wolters Kluwer Medknow Publications
2012-01-01
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Colecção: | Journal of Advanced Pharmaceutical Technology & Research |
Assuntos: | |
Acesso em linha: | http://www.japtr.org/article.asp?issn=2231-4040;year=2012;volume=3;issue=1;spage=30;epage=40;aulast=Singh |
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