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Klotho in Osx+-mesenchymal progenitors exerts pro-osteogenic and anti-inflammatory effects during mandibular alveolar bone formation and repair

Abstract Maxillofacial bone defects are commonly seen in clinical practice. A clearer understanding of the regulatory network directing maxillofacial bone formation will promote the development of novel therapeutic approaches for bone regeneration. The fibroblast growth factor (FGF) signalling pathw...

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Main Authors: Yi Fan, Chen Cui, Clifford J. Rosen, Tadatoshi Sato, Ruoshi Xu, Peiran Li, Xi Wei, Ruiye Bi, Quan Yuan, Chenchen Zhou
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2022-05-01
Colecção:Signal Transduction and Targeted Therapy
Acesso em linha:https://doi.org/10.1038/s41392-022-00957-5
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